Silver- and sulfadiazine-loaded nanostructured silica materials as potential replacement of silver sulfadiazine
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چکیده
منابع مشابه
Properties of silver sulfadiazine-resistant Enterobacter cloacae.
Two silver sulfadiazine-resistant isolates of Enterobacter cloacae obtained in a burns unit where the drug was in use were studied. These strains were resistant to elevated levels of the drug, and they were cross-resistant to silver benzoate, but not to silver nitrate. Growth of the strains in nutritionally poor defined media sensitized them to the inhibitory action of the drug. Exposure of the...
متن کاملSolubility of silver sulfadiazine in physiological media and relevance to treatment of thermal burns with silver sulfadiazine cream.
Silver sulfadiazine cream has been a standard treatment for burns over the past two decades. Although many studies have described the phenomenon of silver absorption from burn wounds treated with silver sulfadiazine, they failed to examine the chemistry underlying the absorption process: Silver chloride was assumed to form at the burn wound and absorption of silver was believed to be negligible...
متن کاملFormulation and In Vitro Evaluation of Silver Sulfadiazine Spray
In order to improve local therapeutic techniques for the massively burnt patients and to minimize the pain associated with dressing change, the concept of topical film was utilized to formulate a topical antimicrobial spray. The commonly used topical antimicrobial silver sulfadiazine spray was formulated as a new drug delivery system. The release of therapeutic agents in vitro from medicated sp...
متن کاملFormulation and In Vitro Evaluation of Silver Sulfadiazine Spray
In order to improve local therapeutic techniques for the massively burnt patients and to minimize the pain associated with dressing change, the concept of topical film was utilized to formulate a topical antimicrobial spray. The commonly used topical antimicrobial silver sulfadiazine spray was formulated as a new drug delivery system. The release of therapeutic agents in vitro from medicated sp...
متن کاملSilver sulfadiazine: effect on the growth and metabolism of bacteria.
Even though the addition of silver sulfadiazine (AgSu) to purified deoxyribonucleic acid (DNA) results in the formation of AgSu-DNA complexes, no such complexes were detected in bacteria treated with AgSu. AgSu blocked macromolecular syntheses in treated bacteria, DNA synthesis being slightly more sensitive to this inhibitory action. The ribosomes, ribonucleic acid, and DNA isolated from treate...
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ژورنال
عنوان ژورنال: J. Mater. Chem. B
سال: 2014
ISSN: 2050-750X,2050-7518
DOI: 10.1039/c4tb00619d